| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DAXX | MDM2 | ENSPANP00000012430 | ENSPANP00000018248 | Death domain associated protein. | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | 0.952 |
| DAXX | PTEN | ENSPANP00000012430 | ENSPANP00000020539 | Death domain associated protein. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.706 |
| DAXX | TP53 | ENSPANP00000012430 | ENSPANP00000033477 | Death domain associated protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.993 |
| DAXX | USP7 | ENSPANP00000012430 | ENSPANP00000038403 | Death domain associated protein. | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. | 0.988 |
| FOXO1 | FOXO3 | ENSPANP00000008419 | ENSPANP00000004459 | Forkhead box O1. | Forkhead box O3. | 0.974 |
| FOXO1 | FOXO4 | ENSPANP00000008419 | ENSPANP00000044448 | Forkhead box O1. | Forkhead box O4. | 0.970 |
| FOXO1 | MDM2 | ENSPANP00000008419 | ENSPANP00000018248 | Forkhead box O1. | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | 0.828 |
| FOXO1 | PTEN | ENSPANP00000008419 | ENSPANP00000020539 | Forkhead box O1. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.737 |
| FOXO1 | TP53 | ENSPANP00000008419 | ENSPANP00000033477 | Forkhead box O1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.864 |
| FOXO1 | USP7 | ENSPANP00000008419 | ENSPANP00000038403 | Forkhead box O1. | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. | 0.969 |
| FOXO3 | FOXO1 | ENSPANP00000004459 | ENSPANP00000008419 | Forkhead box O3. | Forkhead box O1. | 0.974 |
| FOXO3 | FOXO4 | ENSPANP00000004459 | ENSPANP00000044448 | Forkhead box O3. | Forkhead box O4. | 0.969 |
| FOXO3 | MDM2 | ENSPANP00000004459 | ENSPANP00000018248 | Forkhead box O3. | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | 0.836 |
| FOXO3 | PTEN | ENSPANP00000004459 | ENSPANP00000020539 | Forkhead box O3. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.728 |
| FOXO3 | TP53 | ENSPANP00000004459 | ENSPANP00000033477 | Forkhead box O3. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.924 |
| FOXO3 | USP7 | ENSPANP00000004459 | ENSPANP00000038403 | Forkhead box O3. | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. | 0.980 |
| FOXO4 | FOXO1 | ENSPANP00000044448 | ENSPANP00000008419 | Forkhead box O4. | Forkhead box O1. | 0.970 |
| FOXO4 | FOXO3 | ENSPANP00000044448 | ENSPANP00000004459 | Forkhead box O4. | Forkhead box O3. | 0.969 |
| FOXO4 | MDM2 | ENSPANP00000044448 | ENSPANP00000018248 | Forkhead box O4. | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | 0.898 |
| FOXO4 | PTEN | ENSPANP00000044448 | ENSPANP00000020539 | Forkhead box O4. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.654 |
