node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COQ2 | ENSPANP00000035407 | ENSPANP00000007986 | ENSPANP00000035407 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Nudix hydrolase domain-containing protein. | 0.851 |
COQ2 | ENSPANP00000038999 | ENSPANP00000007986 | ENSPANP00000038999 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Uncharacterized protein. | 0.720 |
COQ2 | FDFT1 | ENSPANP00000007986 | ENSPANP00000026951 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Farnesyl-diphosphate farnesyltransferase 1. | 0.755 |
COQ2 | IDI1 | ENSPANP00000007986 | ENSPANP00000019797 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Isopentenyl-diphosphate delta isomerase 1. | 0.851 |
COQ2 | IDI2 | ENSPANP00000007986 | ENSPANP00000044519 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Uncharacterized protein. | 0.851 |
COQ2 | LSS | ENSPANP00000007986 | ENSPANP00000012689 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.773 |
COQ2 | MVD | ENSPANP00000007986 | ENSPANP00000017260 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.524 |
COQ2 | NDUFAF6 | ENSPANP00000007986 | ENSPANP00000010922 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NADH:ubiquinone oxidoreductase complex assembly factor 6. | 0.726 |
ENSPANP00000035407 | COQ2 | ENSPANP00000035407 | ENSPANP00000007986 | Nudix hydrolase domain-containing protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.851 |
ENSPANP00000035407 | ENSPANP00000038999 | ENSPANP00000035407 | ENSPANP00000038999 | Nudix hydrolase domain-containing protein. | Uncharacterized protein. | 0.739 |
ENSPANP00000035407 | FDFT1 | ENSPANP00000035407 | ENSPANP00000026951 | Nudix hydrolase domain-containing protein. | Farnesyl-diphosphate farnesyltransferase 1. | 0.802 |
ENSPANP00000035407 | HMGCS1 | ENSPANP00000035407 | ENSPANP00000011616 | Nudix hydrolase domain-containing protein. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.867 |
ENSPANP00000035407 | HMGCS2 | ENSPANP00000035407 | ENSPANP00000007713 | Nudix hydrolase domain-containing protein. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.810 |
ENSPANP00000035407 | LSS | ENSPANP00000035407 | ENSPANP00000012689 | Nudix hydrolase domain-containing protein. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.930 |
ENSPANP00000035407 | MVD | ENSPANP00000035407 | ENSPANP00000017260 | Nudix hydrolase domain-containing protein. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.966 |
ENSPANP00000035407 | NDUFAF6 | ENSPANP00000035407 | ENSPANP00000010922 | Nudix hydrolase domain-containing protein. | NADH:ubiquinone oxidoreductase complex assembly factor 6. | 0.679 |
ENSPANP00000038999 | COQ2 | ENSPANP00000038999 | ENSPANP00000007986 | Uncharacterized protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.720 |
ENSPANP00000038999 | ENSPANP00000035407 | ENSPANP00000038999 | ENSPANP00000035407 | Uncharacterized protein. | Nudix hydrolase domain-containing protein. | 0.739 |
ENSPANP00000038999 | FDFT1 | ENSPANP00000038999 | ENSPANP00000026951 | Uncharacterized protein. | Farnesyl-diphosphate farnesyltransferase 1. | 0.838 |
ENSPANP00000038999 | HMGCS1 | ENSPANP00000038999 | ENSPANP00000011616 | Uncharacterized protein. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.867 |