STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (489 aa)    
Predicted Functional Partners:
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
0.986
PROCR
Protein C receptor.
    
 0.974
SERPINF2
Serpin family F member 2; Belongs to the serpin family.
   
 0.974
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
    
 0.931
SERPINE1
Serpin family E member 1; Belongs to the serpin family.
    
 0.919
F2R
Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.913
SERPINA5
Serpin family A member 5; Belongs to the serpin family.
   
 0.905
SERPINA1
Alpha-1-antitrypsin; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Inhibits trypsin, chymotrypsin and plasminogen activator (By similarity); Belongs to the serpin family.
   
 0.898
SERPINB2
Serpin peptidase inhibitor, clade B, member 2 (Predicted); Belongs to the serpin family.
   
 0.895
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
   
 0.852
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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