Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF10BTNF receptor superfamily member 10b. (415 aa)    
Predicted Functional Partners:
TNFSF10
TNF superfamily member 10.
    
 0.998
FADD
Fas associated via death domain.
    
 0.997
TNFRSF10A
TNF receptor superfamily member 10a.
  
 
0.990
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.987
CASP8
Caspase 8.
    
 0.976
TRADD
TNFRSF1A associated via death domain.
    
 0.959
CASP10
Caspase 10.
    
 0.898
ENSTGEP00000036544
annotation not available
    
 0.885
CFLAR
CASP8 and FADD like apoptosis regulator.
    
 0.885
FASLG
Fas ligand.
    
 0.880
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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