Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RABGEF1RAB guanine nucleotide exchange factor 1. (491 aa)    
Predicted Functional Partners:
RAB5C
RAB5C, member RAS oncogene family.
   
 0.987
RAB5B
RAB5B, member RAS oncogene family.
   
 0.987
RAB5A
RAB5A, member RAS oncogene family.
   
 0.987
RABEP1
Rabaptin, RAB GTPase binding effector protein 1.
    
 0.949
RABEP2
Rabaptin, RAB GTPase binding effector protein 2.
    
 0.939
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
   
 0.919
RAB24
RAB24, member RAS oncogene family.
   
 0.887
ENSTGEP00000003714
annotation not available
   
 0.878
ZHX2
Zinc fingers and homeoboxes 2.
   
 0.878
ENSTGEP00000012616
annotation not available
   
 0.878
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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