Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SRCSRC proto-oncogene, non-receptor tyrosine kinase. (542 aa)    
Predicted Functional Partners:
FYN
FYN proto-oncogene, Src family tyrosine kinase.
  
0.999
PTK2
Protein tyrosine kinase 2.
   
0.998
SHC1
SHC adaptor protein 1.
   
0.998
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.997
PTK2B
Protein tyrosine kinase 2 beta.
   
0.996
EGFR
Epidermal growth factor receptor.
    
0.996
STAT3
Signal transducer and activator of transcription 3.
   
 0.996
CRK
CRK proto-oncogene, adaptor protein.
   
 0.996
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.996
ESR1
Estrogen receptor 1.
    
 0.996
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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