Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KNL1Kinetochore scaffold 1. (2327 aa)    
Predicted Functional Partners:
ZWINT
ZW10 interacting kinetochore protein.
     
 0.881
CENPE
Centromere protein E.
   
 
 0.811
PRC1
Protein regulator of cytokinesis 1.
   
    0.791
PPP1CA
Protein phosphatase 1 catalytic subunit alpha.
    
  0.769
PPP1CC-2
Protein phosphatase 1 catalytic subunit gamma.
    
  0.769
NDC80
NDC80 kinetochore complex component.
   
 0.754
KIF22
Kinesin family member 22.
   
   0.737
PPP1CC
Protein phosphatase 1 catalytic subunit gamma.
    
  0.737
KIF15
Kinesin family member 15.
   
    0.709
KIF11
Kinesin family member 11.
   
  
 0.687
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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