Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DHHDesert hedgehog signaling molecule. (396 aa)    
Predicted Functional Partners:
HHIP
Hedgehog interacting protein.
    
 0.995
CDON
Cell adhesion associated, oncogene regulated.
    
 0.994
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.993
PTCH1
Patched 1.
   
 0.992
DISP1
Dispatched RND transporter family member 1.
   
 0.988
PTCH2
Patched 2.
   
 0.987
GAS1
Growth arrest specific 1.
    
 0.960
SMO
Smoothened, frizzled class receptor.
    
 0.939
IHH
Indian hedgehog signaling molecule.
  
  
0.937
SHH
Sonic hedgehog signaling molecule.
  
  
 
0.936
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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