Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PPM1BProtein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)    
Predicted Functional Partners:
PPM1A
Protein phosphatase, Mg2+/Mn2+ dependent 1A.
   
   0.988
ENSTGEP00000024127
annotation not available
   
   0.966
ISG15
ISG15 ubiquitin like modifier.
   
 0.955
MAP3K7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.929
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.855
GHRH
Growth hormone releasing hormone.
   
    0.771
ARRB2
Arrestin beta 2.
    
   0.742
TBK1
TANK binding kinase 1.
   
 0.728
PREPL
Prolyl endopeptidase like.
   
  
 0.685
SLC3A1
Solute carrier family 3 member 1.
   
  
 0.682
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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