Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS2DIRAS family GTPase 2. (199 aa)    
Predicted Functional Partners:
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.817
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.751
RNF19B
Ring finger protein 19B.
    
   0.657
ITSN2
Intersectin 2.
    
 0.636
AKR1C3
Aldo-keto reductase family 1 member C3 homolog.
    
 
 0.614
LRRC17
Leucine rich repeat containing 17.
    
 0.613
LEUTX
Leucine twenty homeobox.
      
 0.586
RAP1GAP
RAP1 GTPase activating protein.
    
 0.579
ENSTGEP00000019878
annotation not available
    
 0.579
ENSTGEP00000036553
annotation not available
      
 0.568
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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