HOOK2 protein (Theropithecus gelada) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HOOK2

Hook microtubule tethering protein 2. (719 aa)

Predicted Functional Partners:

AKTIP

0.812

CNTRL

0.613

NIN

0.611

FAM160A1

0.583

HOOK3

0.577

CEP19

0.546

CEP126

0.516

IZUMO4

0.507

FAM160A2

0.502

SUN3

0.490

Your Current Organism:

Theropithecus gelada

NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKTIP	FAM160A1	ENSTGEP00000026954	ENSTGEP00000018289	AKT interacting protein.	Family with sequence similarity 160 member A1.	0.859
AKTIP	FAM160A2	ENSTGEP00000026954	ENSTGEP00000025997	AKT interacting protein.	Family with sequence similarity 160 member A2.	0.889
AKTIP	HOOK2	ENSTGEP00000026954	ENSTGEP00000002003	AKT interacting protein.	Hook microtubule tethering protein 2.	0.812
AKTIP	HOOK3	ENSTGEP00000026954	ENSTGEP00000016012	AKT interacting protein.	Hook microtubule tethering protein 3.	0.892
CEP126	HOOK2	ENSTGEP00000015542	ENSTGEP00000002003	Centrosomal protein 126.	Hook microtubule tethering protein 2.	0.516
CEP19	HOOK2	ENSTGEP00000033682	ENSTGEP00000002003	Centrosomal protein 19.	Hook microtubule tethering protein 2.	0.546
CEP19	NIN	ENSTGEP00000033682	ENSTGEP00000010548	Centrosomal protein 19.	Ninein.	0.558
CNTRL	HOOK2	ENSTGEP00000033096	ENSTGEP00000002003	Centriolin.	Hook microtubule tethering protein 2.	0.613
CNTRL	NIN	ENSTGEP00000033096	ENSTGEP00000010548	Centriolin.	Ninein.	0.630
FAM160A1	AKTIP	ENSTGEP00000018289	ENSTGEP00000026954	Family with sequence similarity 160 member A1.	AKT interacting protein.	0.859
FAM160A1	HOOK2	ENSTGEP00000018289	ENSTGEP00000002003	Family with sequence similarity 160 member A1.	Hook microtubule tethering protein 2.	0.583
FAM160A1	HOOK3	ENSTGEP00000018289	ENSTGEP00000016012	Family with sequence similarity 160 member A1.	Hook microtubule tethering protein 3.	0.779
FAM160A2	AKTIP	ENSTGEP00000025997	ENSTGEP00000026954	Family with sequence similarity 160 member A2.	AKT interacting protein.	0.889
FAM160A2	HOOK2	ENSTGEP00000025997	ENSTGEP00000002003	Family with sequence similarity 160 member A2.	Hook microtubule tethering protein 2.	0.502
FAM160A2	HOOK3	ENSTGEP00000025997	ENSTGEP00000016012	Family with sequence similarity 160 member A2.	Hook microtubule tethering protein 3.	0.868
HOOK2	AKTIP	ENSTGEP00000002003	ENSTGEP00000026954	Hook microtubule tethering protein 2.	AKT interacting protein.	0.812
HOOK2	CEP126	ENSTGEP00000002003	ENSTGEP00000015542	Hook microtubule tethering protein 2.	Centrosomal protein 126.	0.516
HOOK2	CEP19	ENSTGEP00000002003	ENSTGEP00000033682	Hook microtubule tethering protein 2.	Centrosomal protein 19.	0.546
HOOK2	CNTRL	ENSTGEP00000002003	ENSTGEP00000033096	Hook microtubule tethering protein 2.	Centriolin.	0.613
HOOK2	FAM160A1	ENSTGEP00000002003	ENSTGEP00000018289	Hook microtubule tethering protein 2.	Family with sequence similarity 160 member A1.	0.583