STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK4P21 (RAC1) activated kinase 4. (597 aa)    
Predicted Functional Partners:
RAC3
Rac family small GTPase 3.
   
 0.967
ENSTGEP00000033353
annotation not available
   
 0.967
RAC1
Rac family small GTPase 1.
   
 0.960
ITSN2
Intersectin 2.
    
 0.951
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.949
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.949
NCK2
NCK adaptor protein 2.
    
 0.948
NCK1
NCK adaptor protein 1.
    
 0.948
RAC2
Rac family small GTPase 2.
   
 0.948
MAP2K1
Mitogen-activated protein kinase kinase 1.
  
 
0.919
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.