STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSEN2Presenilin 2. (481 aa)    
Predicted Functional Partners:
NCSTN
Nicastrin.
   
 0.998
APH1A
Aph-1 homolog A, gamma-secretase subunit.
   
 0.996
PSEN1
Presenilin 1.
  
 
0.996
APH1B
Aph-1 homolog B, gamma-secretase subunit.
   
 0.995
PSENEN
Presenilin enhancer, gamma-secretase subunit.
    
 0.984
PSENEN-2
Presenilin enhancer, gamma-secretase subunit.
    
 0.984
NOTCH1
Notch receptor 1.
    
 0.981
APP
Amyloid beta precursor protein.
    
 
 0.944
NOTCH3
Notch receptor 3.
    
 0.925
RYR3
Ryanodine receptor 3.
    
 0.918
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.