STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP1poly(ADP-ribose) polymerase 1. (1014 aa)    
Predicted Functional Partners:
CASP3
Caspase 3.
   
 0.982
CASP7
Caspase 7.
   
 0.961
CASP9
Caspase 9.
    
 0.950
POLB
DNA polymerase beta.
    
 0.931
ENSTGEP00000037356
annotation not available
   
 0.931
PARP2
poly(ADP-ribose) polymerase 2.
  
0.927
CHD1L
Chromodomain helicase DNA binding protein 1 like.
   
 0.922
XRCC5
X-ray repair cross complementing 5.
   
 
 0.917
GZMB
Granzyme B.
   
 0.917
PARG
poly(ADP-ribose) glycohydrolase.
    
 0.915
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.