Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PYCR2Pyrroline-5-carboxylate reductase 2. (320 aa)    
Predicted Functional Partners:
PYCR1
Pyrroline-5-carboxylate reductase 1.
  
 
0.998
PYCR3
Pyrroline-5-carboxylate reductase 3.
  
 
 
0.989
ALDH4A1
Aldehyde dehydrogenase 4 family member A1.
   
 
 0.937
PRODH
Proline dehydrogenase 1.
   
 0.933
PRODH2
Proline dehydrogenase 2.
   
 0.928
P4HA2
Prolyl 4-hydroxylase subunit alpha 2.
     
 0.904
NUDT5
Nudix hydrolase 5.
   
   0.904
LAP3
Leucine aminopeptidase 3.
    
 0.904
P4HA3
Prolyl 4-hydroxylase subunit alpha 3.
     
 0.904
P4HA1
Prolyl 4-hydroxylase subunit alpha 1.
     
 0.904
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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