STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMGCL3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)    
Predicted Functional Partners:
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2.
     
 0.953
BDH1
3-hydroxybutyrate dehydrogenase 1.
     
 0.950
ACAA1
acetyl-CoA acyltransferase 1.
  
 
 0.946
IDH3A
Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha.
  
 0.942
IDH3G
Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma.
  
 0.942
IDH3B
Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta.
  
 0.942
ENSTGEP00000027404
annotation not available
  
 0.942
BCAT2
Branched chain amino acid transaminase 2.
  
 0.935
BCAT1
Branched chain amino acid transaminase 1.
  
 0.935
ACAT2
acetyl-CoA acetyltransferase 2.
  
 
 0.935
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.