STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIM2Absent in melanoma 2. (343 aa)    
Predicted Functional Partners:
PYCARD
PYD and CARD domain containing.
    
 0.990
IFI16
Interferon gamma inducible protein 16.
  
 
0.950
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.928
NLRP1
NLR family pyrin domain containing 1.
  
  
 0.802
MEFV
MEFV innate immuity regulator, pyrin.
    
 0.708
NLRC4
NLR family CARD domain containing 4.
   
  
 0.695
CASP1
Caspase 1.
   
 0.685
ENSTGEP00000018929
annotation not available
   
 0.685
CGAS
Cyclic GMP-AMP synthase.
    
 
 0.636
PYHIN1
Pyrin and HIN domain family member 1.
  
 
0.623
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.