STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APAF1Apoptotic peptidase activating factor 1. (1248 aa)    
Predicted Functional Partners:
CASP9
Caspase 9.
    
 0.999
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.991
LOC112611588
Cytochrome c-like.
   
 0.990
LOC112623008
Cytochrome c-like.
   
 0.987
LOC112621297
Cytochrome c.
   
 0.987
CASP3
Caspase 3.
    
 0.984
AVEN
Apoptosis and caspase activation inhibitor.
    
 0.974
APIP
APAF1 interacting protein.
    
 0.954
LOC112620387
Cytochrome c, somatic.
   
 0.941
LOC112605628
Cytochrome c-like.
   
 0.933
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.