STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC6HECT and RLD domain containing E3 ubiquitin protein ligase family member 6. (1021 aa)    
Predicted Functional Partners:
ISG15
ISG15 ubiquitin like modifier.
   
 0.944
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 
 0.911
DDX58
DExD/H-box helicase 58.
   
 
 0.877
IFI44
Interferon induced protein 44.
   
  
 0.872
IFIH1
Interferon induced with helicase C domain 1.
   
 
 0.871
USP18
Ubiquitin specific peptidase 18.
   
 
 0.867
IFIT3
Interferon induced protein with tetratricopeptide repeats 3.
   
 
 0.866
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
 
 0.858
MX1
MX dynamin like GTPase 1.
   
 
 0.855
MX2
MX dynamin like GTPase 2.
   
 
 0.850
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.