STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B2SH2B adaptor protein 2. (680 aa)    
Predicted Functional Partners:
INSR
Insulin receptor.
    
 0.952
CBL
Cbl proto-oncogene.
    
 0.946
CBLB
Cbl proto-oncogene B.
    
 0.914
GRB2
Growth factor receptor bound protein 2.
    
0.911
NTRK1
Neurotrophic receptor tyrosine kinase 1.
    
 0.892
NTRK3
Neurotrophic receptor tyrosine kinase 3.
    
 0.877
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 0.872
JAK2
Janus kinase 2.
    
 0.859
INSRR
Insulin receptor related receptor.
    
 0.779
IGF1R
Insulin like growth factor 1 receptor.
    
 0.779
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.