STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP53BP1Tumor protein p53 binding protein 1. (1977 aa)    
Predicted Functional Partners:
CHEK2
Checkpoint kinase 2.
    
 0.984
ATR
ATR serine/threonine kinase.
    
 0.983
TOPBP1
DNA topoisomerase II binding protein 1.
    
 
 0.977
TP53
Tumor protein p53.
    
 
 0.968
ATM
ATM serine/threonine kinase.
    
 0.967
RNF168
Ring finger protein 168.
    
 0.950
PAXIP1
PAX interacting protein 1.
    
 0.948
BLM
BLM RecQ like helicase.
   
 
 0.943
BRCA1
BRCA1 DNA repair associated.
    
 0.943
CHEK1
Checkpoint kinase 1.
    
 
 0.943
Your Current Organism:
Theropithecus gelada
NCBI taxonomy Id: 9565
Other names: T. gelada, bleeding heart baboon, gelada, gelada baboon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.