STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMLEP00000001028HSF_DOMAIN domain-containing protein. (454 aa)    
Predicted Functional Partners:
HSF1
Heat shock transcription factor 1.
    
 
0.701
SIRT1
Sirtuin 1.
    
 0.652
LOC105530316
CS domain-containing protein.
    
 0.630
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 0.587
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.554
HSF4
Heat shock transcription factor 4.
  
 
 
0.554
MAPKAPK2
MAPK activated protein kinase 2.
    
 0.547
LOC105554720
HATPase_c domain-containing protein.
    
 0.546
HSP90AB1
Heat shock protein 90 alpha family class B member 1.
    
 0.546
ENSMLEP00000011359
Uncharacterized protein.
    
 0.546
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.