Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
ENSMLEP00000001028HSF_DOMAIN domain-containing protein. (454 aa)    
Predicted Functional Partners:
HSF1
Heat shock transcription factor 1.
    
   0.822
HSF4
Heat shock transcription factor 4.
    
   0.806
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 0.681
HSPA4
Heat shock protein family A (Hsp70) member 4.
   
 0.673
HSPBP1
HSPA (Hsp70) binding protein 1.
   
 
 0.664
WDR5
WD repeat domain 5.
    
 
 0.635
LOC105530316
CS domain-containing protein.
    
 0.605
SIRT1
Sirtuin 1.
    
 0.590
MAPKAPK2
MAPK activated protein kinase 2.
    
  0.571
VCP
Valosin containing protein; Belongs to the AAA ATPase family.
     
 0.566
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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