Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F1E2F transcription factor 1. (381 aa)    
Predicted Functional Partners:
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.997
RB1
RB transcriptional corepressor 1.
   
 0.997
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 0.996
RBL1
RB transcriptional corepressor like 1.
   
 0.993
CCNA1
Cyclin A1; Belongs to the cyclin family.
   
 0.993
TFDP1
Transcription factor.
   
 0.991
E2F2
E2F transcription factor 2.
  
 
0.988
E2F3
E2F transcription factor 3.
  
 
0.988
RBL2
RB transcriptional corepressor like 2.
   
 0.984
ENSMLEP00000016498
Transcription factor.
   
 0.957
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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