Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
TMEM106BTransmembrane protein 106B. (274 aa)    
Predicted Functional Partners:
LMAN2L
Lectin, mannose binding 2 like.
    
 
 0.690
TMEM106C
Transmembrane protein 106C.
    
   0.688
GRN
Granulin precursor.
      
 0.603
PSAP
Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
      
 0.594
LMAN2
Lectin, mannose binding 2.
    
 
 0.586
BTNL8
Butyrophilin like 8.
    
   0.528
C9orf72
C9orf72-SMCR8 complex subunit.
      
 0.517
CHMP2B
Charged multivesicular body protein 2B.
    
 
 0.514
EPDR1
Ependymin related 1.
      
 0.502
TMEM239
Transmembrane protein 239.
      
 0.496
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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