STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INPP5AInositol polyphosphate-5-phosphatase A. (408 aa)    
Predicted Functional Partners:
PLCD4
Phosphoinositide phospholipase C.
   
 
 0.993
MINPP1
Multiple inositol-polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family.
     
 0.992
PLCE1
Phosphoinositide phospholipase C.
   
 
 0.944
INPP5J
Inositol polyphosphate-5-phosphatase J.
     
 0.940
INPP5K
Inositol polyphosphate-5-phosphatase K.
     
 0.940
ITPKB
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.940
ITPKA
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.927
ITPKC
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.917
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.913
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.913
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
Server load: low (18%) [HD]