Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SENP8SUMO peptidase family member, NEDD8 specific. (212 aa)    
Predicted Functional Partners:
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.995
ACO1
Aconitase 1; Belongs to the aconitase/IPM isomerase family.
  
 
 0.892
IREB2
Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.
  
 
 0.892
ACO2
Aconitase 2.
  
 
 0.892
ENSMLEP00000036394
Uncharacterized protein.
  
 
 0.892
CUL1
Cullin 1; Belongs to the cullin family.
    
 
 0.873
ACMSD
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.
    
 0.838
PIGL
Phosphatidylinositol glycan anchor biosynthesis class L.
    
 0.837
PSTPIP2
Proline-serine-threonine phosphatase interacting protein 2.
    
   0.783
TRMT5
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.
    
   0.770
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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