Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIFM1Apoptosis inducing factor mitochondria associated 1. (613 aa)    
Predicted Functional Partners:
BAX
BCL2 associated X, apoptosis regulator.
    
 0.926
EXOG
Exo/endonuclease G.
    
 
 0.882
GSR
Glutathione-disulfide reductase.
  
 0.881
LOC105553468
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 0.865
PPIA
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 0.865
DLD
Dihydrolipoyl dehydrogenase.
  
 0.850
ENSMLEP00000005039
CHCH domain-containing protein.
    
 
 0.829
CHCHD4
CHCH domain-containing protein.
    
 
 0.829
ENSMLEP00000005144
Thioredoxin; Belongs to the thioredoxin family.
    
 
 0.818
TXN
Thioredoxin domain-containing protein.
    
 
 0.818
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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