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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)    
Predicted Functional Partners:
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 0.991
CD8A
CD8a molecule.
    
 0.983
KLRD1
Killer cell lectin like receptor D1.
    
 0.983
TAPBP
TAP binding protein.
   
 0.974
CALR
Calreticulin.
    
 0.958
ENSMLEP00000003171
C-type lectin domain-containing protein.
    
 0.956
PDIA3
Protein disulfide-isomerase.
    
 0.955
ENSMLEP00000016260
MHC_I-like_Ag-recog domain-containing protein.
  
0.949
KIR2DL4
Uncharacterized protein.
    
 0.944
CD8B
Ig-like domain-containing protein.
     
 0.930
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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