STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (598 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.969
XPC
XPC complex subunit, DNA damage recognition and repair factor.
   
 0.865
CUL4B
Cullin 4B; Belongs to the cullin family.
    
 0.809
CUL4A
Cullin 4A; Belongs to the cullin family.
    
 0.809
COPS8
COP9 signalosome subunit 8.
    
 0.798
HELLS
Helicase, lymphoid specific.
   
 0.797
COPS4
COP9 signalosome subunit 4.
    
 0.796
RPA2
Replication protein A2.
    
 0.783
DCAF8
DDB1 and CUL4 associated factor 8.
    
 0.777
COPS2
COP9 signalosome subunit 2.
    
 0.770
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.