STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR83WD repeat domain 83. (315 aa)    
Predicted Functional Partners:
LAMTOR3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
   
 0.947
SF3B4
Splicing factor 3b subunit 4.
    
 
 0.937
GPATCH1
G-patch domain containing 1.
    
 
 0.920
PRPF8
Pre-mRNA processing factor 8.
    
   0.905
AQR
RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
    
 
 0.630
CDC40
Cell division cycle 40.
  
 
  
0.612
CCDC12
Coiled-coil domain containing 12.
    
 
 0.596
CWF19L2
CWF19 like cell cycle control factor 2.
   
 
 0.592
SYF2
SYF2 pre-mRNA splicing factor.
    
   0.580
DHX35
DEAH-box helicase 35.
    
   0.577
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.