STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEPHHephaestin; Belongs to the multicopper oxidase family. (1212 aa)    
Predicted Functional Partners:
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
   
 
 0.929
HMOX1
Heme oxygenase 1.
    
 0.902
HMOX2
Heme oxygenase 2.
    
 0.899
CP
Ceruloplasmin; Belongs to the multicopper oxidase family.
  
  
 
0.893
SLC40A1
Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
    
 0.891
ENSMLEP00000002569
Uncharacterized protein.
     
 0.880
FXN
Frataxin.
     
 0.880
NCOA4
Nuclear receptor coactivator 4.
      
 0.607
ATP7A
ATPase copper transporting alpha.
  
 
 0.564
ATP7B
ATPase copper transporting beta.
  
 
 0.564
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.