| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AASDH | ASMTL | ENSMLEP00000028032 | ENSMLEP00000023603 | Aminoadipate-semialdehyde dehydrogenase. | Acetylserotonin O-methyltransferase like. | 0.544 |
| AASDH | CYP11A1 | ENSMLEP00000028032 | ENSMLEP00000008703 | Aminoadipate-semialdehyde dehydrogenase. | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 0.580 |
| AASDH | CYP11B1 | ENSMLEP00000028032 | ENSMLEP00000032436 | Aminoadipate-semialdehyde dehydrogenase. | Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.580 |
| AASDH | CYP4B1 | ENSMLEP00000028032 | ENSMLEP00000013228 | Aminoadipate-semialdehyde dehydrogenase. | Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.586 |
| AASDH | CYP4F3 | ENSMLEP00000028032 | ENSMLEP00000024400 | Aminoadipate-semialdehyde dehydrogenase. | Cytochrome P450 family 4 subfamily F member 3. | 0.586 |
| AASDH | EPHX2 | ENSMLEP00000028032 | ENSMLEP00000010456 | Aminoadipate-semialdehyde dehydrogenase. | Epoxide hydrolase 2. | 0.718 |
| AASDH | LOC105536288 | ENSMLEP00000028032 | ENSMLEP00000033011 | Aminoadipate-semialdehyde dehydrogenase. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.580 |
| AASDH | LOC105539005 | ENSMLEP00000028032 | ENSMLEP00000001623 | Aminoadipate-semialdehyde dehydrogenase. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.554 |
| AASDH | SUOX | ENSMLEP00000028032 | ENSMLEP00000040734 | Aminoadipate-semialdehyde dehydrogenase. | Sulfite oxidase. | 0.634 |
| ASMTL | AASDH | ENSMLEP00000023603 | ENSMLEP00000028032 | Acetylserotonin O-methyltransferase like. | Aminoadipate-semialdehyde dehydrogenase. | 0.544 |
| ASMTL | CYP11A1 | ENSMLEP00000023603 | ENSMLEP00000008703 | Acetylserotonin O-methyltransferase like. | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 0.609 |
| ASMTL | CYP11B1 | ENSMLEP00000023603 | ENSMLEP00000032436 | Acetylserotonin O-methyltransferase like. | Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.609 |
| ASMTL | CYP4B1 | ENSMLEP00000023603 | ENSMLEP00000013228 | Acetylserotonin O-methyltransferase like. | Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.645 |
| ASMTL | CYP4F3 | ENSMLEP00000023603 | ENSMLEP00000024400 | Acetylserotonin O-methyltransferase like. | Cytochrome P450 family 4 subfamily F member 3. | 0.645 |
| ASMTL | LOC105536288 | ENSMLEP00000023603 | ENSMLEP00000033011 | Acetylserotonin O-methyltransferase like. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.609 |
| ASMTL | LOC105539005 | ENSMLEP00000023603 | ENSMLEP00000001623 | Acetylserotonin O-methyltransferase like. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.728 |
| ASMTL | SUOX | ENSMLEP00000023603 | ENSMLEP00000040734 | Acetylserotonin O-methyltransferase like. | Sulfite oxidase. | 0.577 |
| CYP11A1 | AASDH | ENSMLEP00000008703 | ENSMLEP00000028032 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Aminoadipate-semialdehyde dehydrogenase. | 0.580 |
| CYP11A1 | ASMTL | ENSMLEP00000008703 | ENSMLEP00000023603 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Acetylserotonin O-methyltransferase like. | 0.609 |
| CYP11A1 | LOC105539005 | ENSMLEP00000008703 | ENSMLEP00000001623 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.557 |