TLR9 protein (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TLR9

TIR domain-containing protein. (1033 aa)

Predicted Functional Partners:

MYD88

0.992

TLR7

0.976

TIRAP

0.959

TICAM1

0.952

TICAM2

0.941

TLR4

0.939

TLR2

0.921

TLR3

0.809

UNC93B1

0.789

TLR8

0.771

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYD88	TICAM1	ENSMLEP00000015569	ENSMLEP00000028900	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor adaptor molecule 1.	0.570
MYD88	TICAM2	ENSMLEP00000015569	ENSMLEP00000006968	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor adaptor molecule 2.	0.433
MYD88	TIRAP	ENSMLEP00000015569	ENSMLEP00000039140	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TIR domain containing adaptor protein.	0.995
MYD88	TLR2	ENSMLEP00000015569	ENSMLEP00000000183	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll-like receptor.	0.991
MYD88	TLR3	ENSMLEP00000015569	ENSMLEP00000028707	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor 3; Belongs to the Toll-like receptor family.	0.938
MYD88	TLR4	ENSMLEP00000015569	ENSMLEP00000013603	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.996
MYD88	TLR7	ENSMLEP00000015569	ENSMLEP00000033999	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor 7; Belongs to the Toll-like receptor family.	0.991
MYD88	TLR8	ENSMLEP00000015569	ENSMLEP00000026501	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor 8; Belongs to the Toll-like receptor family.	0.987
MYD88	TLR9	ENSMLEP00000015569	ENSMLEP00000001736	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TIR domain-containing protein.	0.992
MYD88	UNC93B1	ENSMLEP00000015569	ENSMLEP00000025892	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Unc-93 homolog B1, TLR signaling regulator.	0.490
TICAM1	MYD88	ENSMLEP00000028900	ENSMLEP00000015569	Toll like receptor adaptor molecule 1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.570
TICAM1	TICAM2	ENSMLEP00000028900	ENSMLEP00000006968	Toll like receptor adaptor molecule 1.	Toll like receptor adaptor molecule 2.	0.978
TICAM1	TIRAP	ENSMLEP00000028900	ENSMLEP00000039140	Toll like receptor adaptor molecule 1.	TIR domain containing adaptor protein.	0.547
TICAM1	TLR2	ENSMLEP00000028900	ENSMLEP00000000183	Toll like receptor adaptor molecule 1.	Toll-like receptor.	0.965
TICAM1	TLR3	ENSMLEP00000028900	ENSMLEP00000028707	Toll like receptor adaptor molecule 1.	Toll like receptor 3; Belongs to the Toll-like receptor family.	0.995
TICAM1	TLR4	ENSMLEP00000028900	ENSMLEP00000013603	Toll like receptor adaptor molecule 1.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.993
TICAM1	TLR7	ENSMLEP00000028900	ENSMLEP00000033999	Toll like receptor adaptor molecule 1.	Toll like receptor 7; Belongs to the Toll-like receptor family.	0.566
TICAM1	TLR8	ENSMLEP00000028900	ENSMLEP00000026501	Toll like receptor adaptor molecule 1.	Toll like receptor 8; Belongs to the Toll-like receptor family.	0.526
TICAM1	TLR9	ENSMLEP00000028900	ENSMLEP00000001736	Toll like receptor adaptor molecule 1.	TIR domain-containing protein.	0.952
TICAM2	MYD88	ENSMLEP00000006968	ENSMLEP00000015569	Toll like receptor adaptor molecule 2.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.433