OLIG2 protein (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

OLIG2

Oligodendrocyte transcription factor 2. (192 aa)

Predicted Functional Partners:

SOX8

0.694

NKX2-2

0.692

GFAP

0.684

NES

0.634

BDNF

0.632

CNP

0.631

MBP

0.611

NRG1

0.599

PAX6

0.597

MOG

0.595

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	CNP	ENSMLEP00000026456	ENSMLEP00000038107	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	0.440
BDNF	GFAP	ENSMLEP00000026456	ENSMLEP00000026563	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.703
BDNF	MBP	ENSMLEP00000026456	ENSMLEP00000035274	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Myelin basic protein.	0.465
BDNF	NES	ENSMLEP00000026456	ENSMLEP00000021277	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Nestin; Belongs to the intermediate filament family.	0.689
BDNF	NRG1	ENSMLEP00000026456	ENSMLEP00000020694	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Neuregulin 1.	0.656
BDNF	OLIG2	ENSMLEP00000026456	ENSMLEP00000001742	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Oligodendrocyte transcription factor 2.	0.632
BDNF	PAX6	ENSMLEP00000026456	ENSMLEP00000011841	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Paired box 6.	0.424
CNP	BDNF	ENSMLEP00000038107	ENSMLEP00000026456	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	0.440
CNP	GFAP	ENSMLEP00000038107	ENSMLEP00000026563	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.605
CNP	MBP	ENSMLEP00000038107	ENSMLEP00000035274	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	Myelin basic protein.	0.715
CNP	MOG	ENSMLEP00000038107	ENSMLEP00000035410	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	Myelin oligodendrocyte glycoprotein.	0.679
CNP	NES	ENSMLEP00000038107	ENSMLEP00000021277	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	Nestin; Belongs to the intermediate filament family.	0.462
CNP	OLIG2	ENSMLEP00000038107	ENSMLEP00000001742	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	Oligodendrocyte transcription factor 2.	0.631
GFAP	BDNF	ENSMLEP00000026563	ENSMLEP00000026456	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	0.703
GFAP	CNP	ENSMLEP00000026563	ENSMLEP00000038107	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family.	0.605
GFAP	MBP	ENSMLEP00000026563	ENSMLEP00000035274	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Myelin basic protein.	0.685
GFAP	MOG	ENSMLEP00000026563	ENSMLEP00000035410	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Myelin oligodendrocyte glycoprotein.	0.533
GFAP	NES	ENSMLEP00000026563	ENSMLEP00000021277	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Nestin; Belongs to the intermediate filament family.	0.918
GFAP	NRG1	ENSMLEP00000026563	ENSMLEP00000020694	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Neuregulin 1.	0.423
GFAP	OLIG2	ENSMLEP00000026563	ENSMLEP00000001742	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Oligodendrocyte transcription factor 2.	0.684