STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OLIG2Oligodendrocyte transcription factor 2. (192 aa)    
Predicted Functional Partners:
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  
 0.706
PAX6
Paired box 6.
   
 
 0.656
SOX10
SRY-box transcription factor 10.
   
 0.656
MBP
Myelin basic protein.
   
  
 0.638
ASCL1
Achaete-scute family bHLH transcription factor 1.
   
 
 0.600
NES
Nestin; Belongs to the intermediate filament family.
      
 0.589
PDGFRA
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
      
 0.588
NKX2-2
NK2 homeobox 2.
   
 0.584
DLX2
Distal-less homeobox 2.
   
  
 0.562
DCX
Doublecortin.
      
 0.548
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.