Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLCN5Chloride channel protein. (816 aa)    
Predicted Functional Partners:
CLCN3
Chloride channel protein.
  
 
0.997
CLCN4
Chloride channel protein.
  
 
0.993
TMEM9B
TMEM9 domain family member B.
    
 
 0.854
LOC105535206
Uncharacterized protein.
    
 
 0.795
OCRL
OCRL inositol polyphosphate-5-phosphatase.
   
  
 0.667
OSTM1
Osteoclastogenesis associated transmembrane protein 1.
    
 0.644
LRP2
LDL receptor related protein 2.
      
 0.583
CUBN
Cubilin.
      
 0.582
GPR153
G protein-coupled receptor 153.
      
 0.582
SLC34A3
Solute carrier family 34 member 3.
      
 0.581
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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