Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TACC1Transforming acidic coiled-coil containing protein 1. (806 aa)    
Predicted Functional Partners:
CKAP5
Cytoskeleton associated protein 5.
    
 0.912
TACC2
Transforming acidic coiled-coil containing protein 2.
    
 
 0.861
PLXNB2
Plexin B2.
    
  0.828
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
   0.824
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
    
 0.806
VAPA
MSP domain-containing protein.
    
  0.776
NIF3L1
NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
    
   0.772
LSM7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.
   
 
 0.730
LOC105544059
MSP domain-containing protein.
    
  0.707
VAPB
VAMP associated protein B and C.
    
  0.704
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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