STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (398 aa)    
Predicted Functional Partners:
PTCH2
Patched 2.
   
 0.998
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.990
CDON
Cell adhesion associated, oncogene regulated.
    
 0.990
PTCH1
Patched 1.
   
 0.986
HHIP
Hedgehog interacting protein.
    
 0.982
DISP1
Dispatched RND transporter family member 1.
   
 0.930
LRP2
LDL receptor related protein 2.
     
 0.921
GPC3
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.915
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
  
  
0.891
DISP2
Dispatched RND transporter family member 2.
    
 0.880
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.