Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SERPINA12Serpin family A member 12; Belongs to the serpin family. (414 aa)    
Predicted Functional Partners:
CYB5R4
Cytochrome b5 reductase 4.
    
   0.732
SPATA7
Spermatogenesis associated 7.
    
   0.732
DENND1B
DENN domain containing 1B.
    
   0.639
GPER1
G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
 0.628
MMP15
Matrix metallopeptidase 15.
    
 0.566
PROC
Uncharacterized protein; Belongs to the peptidase S1 family.
   
  0.560
KLK7
Kallikrein related peptidase 7; Belongs to the peptidase S1 family.
   
 0.533
KRT77
Keratin 77; Belongs to the intermediate filament family.
   
 
 0.529
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.529
WEE2
Wee1-like protein kinase.
      
 0.505
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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