Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM49BFamily with sequence similarity 49 member B. (324 aa)    
Predicted Functional Partners:
FAM49A
Family with sequence similarity 49 member A.
  
 
0.997
RAC1
Uncharacterized protein.
    
 0.928
ENSMLEP00000001022
Uncharacterized protein.
    
 0.928
RAC2
Rac family small GTPase 2.
    
 0.928
RAC3
Rac family small GTPase 3.
    
 0.928
KLHL7
Kelch like family member 7.
      
 0.588
TASP1
Taspase 1.
      
 0.579
GRTP1
Growth hormone regulated TBC protein 1.
      
 0.535
DDX1
DEAD-box helicase 1.
      
 0.500
RBFOX1
RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events.
      
 0.498
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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