Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZC3H4Zinc finger CCCH-type containing 4. (1249 aa)    
Predicted Functional Partners:
ENSMLEP00000015784
Uncharacterized protein.
   
 0.958
WDR82
WD repeat domain 82.
   
 0.958
ZC3H6
Zinc finger CCCH-type containing 6.
    
 
 0.842
SYMPK
Symplekin.
   
 0.812
CPSF1
Cleavage and polyadenylation specific factor 1.
   
 0.812
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.807
NUDT21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
    
 0.807
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.804
RBBP6
RB binding protein 6, ubiquitin ligase.
   
 0.801
FIP1L1
Factor interacting with PAPOLA and CPSF1.
    
 0.799
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.