STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNX3Sorting nexin 3. (145 aa)    
Predicted Functional Partners:
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.984
VPS26A
VPS26, retromer complex component A.
    
 0.979
VPS26B
VPS26, retromer complex component B.
   
 0.950
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.874
SNX15
Sorting nexin 15.
     
 0.771
ENSMLEP00000004732
Uncharacterized protein.
     
 0.771
SNX12
Sorting nexin 12.
  
 
 
0.765
WLS
Wnt ligand secretion mediator.
    
 0.731
RPS6KC1
Ribosomal protein S6 kinase C1.
     
 0.710
SNX27
Sorting nexin 27.
    
 0.674
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.