Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1012 aa)    
Predicted Functional Partners:
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
    
 0.997
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.996
ENSMLEP00000022361
Uncharacterized protein; Belongs to the heat shock protein 70 family.
    
 0.975
NFE2L2
Nuclear factor, erythroid 2 like 2.
   
 0.973
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
0.957
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
0.957
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
     
 0.915
DNAJC3
DnaJ heat shock protein family (Hsp40) member C3.
   
 0.912
PSEN2
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
     
 0.906
IFIT1B
Interferon induced protein with tetratricopeptide repeats 1B.
   
  0.904
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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