STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHACTR1Phosphatase and actin regulator. (484 aa)    
Predicted Functional Partners:
ACTA1
Actin alpha 1, skeletal muscle.
    
   0.877
CACNA1I
Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]
      
 0.635
ACTC1
Actin alpha cardiac muscle 1.
    
   0.604
ANKS1A
Ankyrin repeat and sterile alpha motif domain containing 1A.
   
  
 0.590
ANKS1B
Ankyrin repeat and sterile alpha motif domain containing 1B.
   
  
 0.572
PDE1A
Phosphodiesterase.
      
 0.562
DLEU7
Deleted in lymphocytic leukemia 7.
      
 0.562
ACTL10
Actin like 10; Belongs to the actin family.
    
   0.557
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 
 0.542
PLCH1
Phosphoinositide phospholipase C.
      
 0.525
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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