STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKLE2Ankyrin repeat and LEM domain containing 2. (904 aa)    
Predicted Functional Partners:
SIRT2
Sirtuin 2.
    
 0.858
VRK1
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
   
 0.844
VRK2
VRK serine/threonine kinase 2.
   
 0.844
PPP2R1A
Protein phosphatase 2 scaffold subunit Aalpha.
    
  0.821
PPP2CB
Serine/threonine-protein phosphatase.
    
  0.769
PPP2CA
Serine/threonine-protein phosphatase.
    
  0.755
ENSMLEP00000001956
Uncharacterized protein.
    
 0.714
BANF1
Uncharacterized protein.
    
 0.714
ENSMLEP00000020589
Uncharacterized protein.
    
 0.714
LRIG2
Leucine rich repeats and immunoglobulin like domains 2.
    
 0.713
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.