STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD70TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (316 aa)    
Predicted Functional Partners:
CD27
CD27 molecule.
    
 0.999
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
      
 0.804
CD19
CD19 molecule.
  
   
 0.581
CD22
CD22 molecule.
  
   
 0.569
CD40
CD40 molecule.
   
  
 0.563
CD80
CD80 molecule.
      
 0.561
CD4
CD4 molecule.
      
 0.556
TNFRSF4
TNF receptor superfamily member 4.
   
  
 0.551
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
      
 0.540
CD33
CD33 molecule.
      
 0.535
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.