STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)    
Predicted Functional Partners:
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.914
SLC2A4
Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
  
0.895
SLC2A2
Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
  
 
0.892
RAB14
RAB14, member RAS oncogene family.
     
 0.632
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
      
 0.607
CYB5R4
Cytochrome b5 reductase 4.
   
 
  0.584
ASPSCR1
ASPSCR1 tether for SLC2A4, UBX domain containing.
    
 0.575
TNIK
TRAF2 and NCK interacting kinase.
   
 
  0.554
SLC7A5
Solute carrier family 7 member 5.
   
 
 0.532
BSG
Basigin (Ok blood group).
    
 
 0.510
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.