SARM1 protein (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SARM1

Sterile alpha and TIR motif containing 1. (454 aa)

Predicted Functional Partners:

TRAF6

0.627

TICAM1

0.627

MYD88

0.621

PINK1

0.587

NMNAT2

0.575

TLR4

0.556

ENPP1

0.553

TLR3

0.530

NMNAT3

0.515

TIRAP

0.512

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENPP1	NMNAT2	ENSMLEP00000014059	ENSMLEP00000032498	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	Nicotinamide nucleotide adenylyltransferase 2.	0.992
ENPP1	NMNAT3	ENSMLEP00000014059	ENSMLEP00000008827	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	Nicotinamide-nucleotide adenylyltransferase.	0.992
ENPP1	SARM1	ENSMLEP00000014059	ENSMLEP00000004335	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	Sterile alpha and TIR motif containing 1.	0.553
MYD88	SARM1	ENSMLEP00000015569	ENSMLEP00000004335	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Sterile alpha and TIR motif containing 1.	0.621
MYD88	TICAM1	ENSMLEP00000015569	ENSMLEP00000028900	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor adaptor molecule 1.	0.532
MYD88	TIRAP	ENSMLEP00000015569	ENSMLEP00000039140	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TIR domain containing adaptor protein.	0.989
MYD88	TLR3	ENSMLEP00000015569	ENSMLEP00000028707	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor 3; Belongs to the Toll-like receptor family.	0.938
MYD88	TLR4	ENSMLEP00000015569	ENSMLEP00000013603	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.997
MYD88	TRAF6	ENSMLEP00000015569	ENSMLEP00000002468	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.994
NMNAT2	ENPP1	ENSMLEP00000032498	ENSMLEP00000014059	Nicotinamide nucleotide adenylyltransferase 2.	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	0.992
NMNAT2	NMNAT3	ENSMLEP00000032498	ENSMLEP00000008827	Nicotinamide nucleotide adenylyltransferase 2.	Nicotinamide-nucleotide adenylyltransferase.	0.992
NMNAT2	SARM1	ENSMLEP00000032498	ENSMLEP00000004335	Nicotinamide nucleotide adenylyltransferase 2.	Sterile alpha and TIR motif containing 1.	0.575
NMNAT3	ENPP1	ENSMLEP00000008827	ENSMLEP00000014059	Nicotinamide-nucleotide adenylyltransferase.	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	0.992
NMNAT3	NMNAT2	ENSMLEP00000008827	ENSMLEP00000032498	Nicotinamide-nucleotide adenylyltransferase.	Nicotinamide nucleotide adenylyltransferase 2.	0.992
NMNAT3	SARM1	ENSMLEP00000008827	ENSMLEP00000004335	Nicotinamide-nucleotide adenylyltransferase.	Sterile alpha and TIR motif containing 1.	0.515
PINK1	SARM1	ENSMLEP00000029199	ENSMLEP00000004335	PTEN induced kinase 1.	Sterile alpha and TIR motif containing 1.	0.587
SARM1	ENPP1	ENSMLEP00000004335	ENSMLEP00000014059	Sterile alpha and TIR motif containing 1.	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	0.553
SARM1	MYD88	ENSMLEP00000004335	ENSMLEP00000015569	Sterile alpha and TIR motif containing 1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.621
SARM1	NMNAT2	ENSMLEP00000004335	ENSMLEP00000032498	Sterile alpha and TIR motif containing 1.	Nicotinamide nucleotide adenylyltransferase 2.	0.575
SARM1	NMNAT3	ENSMLEP00000004335	ENSMLEP00000008827	Sterile alpha and TIR motif containing 1.	Nicotinamide-nucleotide adenylyltransferase.	0.515