STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KMT5ALysine methyltransferase 5A. (313 aa)    
Predicted Functional Partners:
SETD7
Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
   
 0.866
CENPA
Centromere protein A.
   
 0.861
H2AC6
Histone H2A; Belongs to the histone H2A family.
    
 0.860
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3.
    
  0.831
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 0.830
SMYD2
SET and MYND domain containing 2.
    
 0.796
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.787
KMT2E
Lysine methyltransferase 2E.
    
 0.781
SETD5
SET domain containing 5.
   
 0.771
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
   0.760
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.