STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM28ADAM metallopeptidase domain 28. (774 aa)    
Predicted Functional Partners:
LGI1
Leucine rich glioma inactivated 1.
    
 0.622
CNBD1
Cyclic nucleotide binding domain containing 1.
      
 0.572
STK38L
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
      
 0.544
ZFYVE1
Zinc finger FYVE-type containing 1.
      
 0.541
ADAM22
ADAM metallopeptidase domain 22.
    
 
0.525
TSC22D1
TSC22 domain family member 1.
    
 
 0.498
TMEFF2
Transmembrane protein with EGF like and two follistatin like domains 2.
      
 0.485
USP33
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
      
 0.485
MANEA
Mannosidase endo-alpha.
    
 0.443
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.