Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM28ADAM metallopeptidase domain 28. (774 aa)    
Predicted Functional Partners:
LGI1
Leucine rich glioma inactivated 1.
    
 0.576
ADAM22
ADAM metallopeptidase domain 22.
    
 
 0.502
LGI2
Leucine rich repeat LGI family member 2.
     
 0.436
PTPRK
Protein tyrosine phosphatase receptor type K.
     
 0.431
VSIG4
V-set and immunoglobulin domain containing 4.
      
 0.423
FAM160B2
Family with sequence similarity 160 member B2.
      
 0.422
ZNF511
Zinc finger protein 511.
      
 0.416
CST11
Cystatin 11.
   
  
 0.415
SCN1B
Sodium voltage-gated channel beta subunit 1.
      
 0.415
OVCH2
Ovochymase 2 (gene/pseudogene); Belongs to the peptidase S1 family.
   
  
 0.404
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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