STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP10Poly [ADP-ribose] polymerase. (950 aa)    
Predicted Functional Partners:
RNF146
Ring finger protein 146.
      
 0.609
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
    
 
 0.534
TRPT1
tRNA phosphotransferase 1.
     
 0.523
PARP2
Poly [ADP-ribose] polymerase.
    
 
 0.514
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.512
NUP205
Nucleoporin 205.
      
 0.510
GRINA
Glutamate ionotropic receptor NMDA type subunit associated protein 1.
   
  
 0.492
LRPPRC
Leucine rich pentatricopeptide repeat containing.
      
 0.491
MCM5
DNA helicase; Belongs to the MCM family.
      
 0.487
CNN3
Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
   
  
 0.486
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.